PWE-086 Determining Stem Cell And Crypt Dynamics In Inflammatory Bowel Disease
نویسندگان
چکیده
منابع مشابه
Effects of Probiotics and Prebiotics in Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) including most important forms; Crohn’s disease (CD) and ulcerative colitis (UC); are chronic diseases affecting the gastrointestinal tract with unclear etiology and pathology. The role of gut microbiota has recently been considered as major a factor, since altered microbiome or "dysbiosis" is a key player in the protracted course of inflammation in IBD. Howeve...
متن کاملStem Cell Therapy in the Treatment of Inflammatory Bowel Disease
IBD: Inflammatory Bowel Disease ; UC: Ulcerative Colitis; CD: Crohn’s Diseases; TNF-α: Tumor Necrosis Factor α; IL12/23: Interleukin 12/23; IL-6R: Interleukin 6R; iRNA: information Ribonucleic acid; SC: Stem Cells; CT: Cell Therapy; MSC: Mesenchymal Stem Cells; HSC: Hematopoietic Stem Cells; 2,4,6-TNBA: 2,4,6-Trinitrobenzene Sulfonic Acid; SDF-1: Stromal Derived Factor-1; VEGF: Vasculoendotheli...
متن کاملImprovement of inflammatory bowel disease after allogeneic stem-cell transplantation.
Because causes of inflammatory bowel disease (IBD) remain obscure and a curative therapy is still lacking, the influence of stem-cell transplantation (SCT) on IBD is of major interest. We retrospectively analyzed the course of seven patients with Crohn's disease and four patients with idiopathic ulcerative colitis who underwent allogeneic SCT between July 1994 and August 2002 for acute and chro...
متن کاملInflammatory bowel disease: Moving toward a stem cell-based therapy.
The incidence and prevalence of Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammatory bowel diseases (IBD), are rising in western countries. The modern hygienic lifestyle is probably at the root of a disease where, in genetically susceptible hosts, the intestinal commensal flora triggers dysregulated immune and inflammatory responses. Current therapies ranging fr...
متن کاملNeonatal Presentation of Unremitting Inflammatory Bowel Disease
Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 2014
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2014-307263.346